By A. Hjalmarsson,W.J. Remme

ISBN-10: 0387913939

ISBN-13: 9780387913933

even though surgical and catheter-based revascularization ideas have substan­ tially greater modern-day healing capability in ischemic center ailment, within the majority of sufferers therapy can be conservative for a few purposes, the cost-effectiveness of non-pharmacological methods being of significant value. over the last twenty years, drug improvement for ischemic middle disorder has been striking and lots of new compounds were extra to our healing armamentarium. however, the place mode of motion is anxious, it's fascinating to notice that, regardless of these kinds of efforts, we're nonetheless restricted to 3 different types of substances. Antithrombotics and platelet-active brokers apart, those difficulty nitrates, betablocking medications and calcium antagonists, brokers which lessen ischemia by means of diminishing cardiac paintings or wall stress,. thereby affecting myocardial oxygen call for and/or through enhancing coronary blood circulation. on my own or together, those brokers have proved to be efficacious within the remedy of angina pectoris or different indicators of ischemic middle affliction in a few sufferers, yet by no means in all. furthermore, as side-effects are usually an issue with present antianginal compounds, the surgeon may possibly locate himself limited in his healing functions and short of new and, ideally, substitute different types of pharmacological treatment.

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Sinus node inhibitors: A new concept in angina pectoris by A. Hjalmarsson,W.J. Remme


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